How do pre-existing immunity and host factors interact to impact influenza vaccine response?

A scatterplot showing fold change in HAI titer vs. prevaccination titer. While all of our plots show the expected negative linear response, the effect of age is typically quite noticeable.

I presented a poster at the Ecology and Evolution of Infectious Disease conference in 2021. The conference was supposed to be held in Montpellier, France, but due to the COVID-19 pandemic was held virtually in That was an interesting experience.

The poster can be found here, and is also embedded below. We are continuing our exploration of vaccine cohort data to determine what mechanistic model predictions can be verified by data, and what aspects of mechanistic models may need to be adapted.