Exploring the effect of host factors on the relationship between pre-existing immunity and influenza vaccine response

A scatterplot showing one of our interesting findings: while the previous mechanistic models did not account for age, we see clear patterns in the distribution of age when we plot fold change vs. prevaccination titer.

I presented a poster at the Ecology and Evolution of Infectious Disease conference in 2021. The conference was supposed to be held in Montpellier, France, but due to the COVID-19 pandemic was held virtually in gather.town. That was an interesting experience.

The poster can be found here, and is also embedded below. We are continuing our exploration of vaccine cohort data to determine what mechanistic model predictions can be verified by data, and what aspects of mechanistic models may need to be adapted.